Active principles 100 g of powder contain: Magnesia S. Pellegrino 90% powder for oral suspension Active ingredient: magnesium hydroxide 90 g Excipients: sucrose. Magnesia S. Pellegrino 45% effervescent powder Active ingredient: magnesium hydroxide 45 g Excipients: sucrose. For the full list of excipients, see section 6.1. Excipients Magnesia S. Pellegrino powder 90% for oral suspension: without flavor: sucrose. lemon flavor: sucrose, natural lemon flavor. Magnesia S. Pellegrino 45% effervescent powder: without aroma: sodium bicarbonate, tartaric acid, sucrose. anise flavor: sodium bicarbonate, tartaric acid, sucrose, anethole. fruit flavor: sodium bicarbonate, tartaric acid, sucrose, natural fruit flavor. lemon flavor: sodium bicarbonate, tartaric acid, sucrose, natural lemon flavor. mandarin flavor: sodium bicarbonate, tartaric acid, sucrose, natural mandarin flavoring. Therapeutic indications Short-term treatment of occasional constipation. Antacid. Active principles 45% effervescent powder: magnesium hydroxide 45g. Excipients Sodium bicarbonate, tartaric acid, sucrose, natural lemon flavor. Tangerine flavor: sodium bicarbonate, tartaric acid, sucrose, natural mandarin flavoring. Contraindications / Side Effects Hypersensitivity 'to the active substance or to any of the excipients. Laxatives are contraindicated in subjects with acute abdominal pain or of unknown origin, nausea or vomiting, intestinal obstruction or stenosis, rectal bleeding of unknown origin, severe dehydration. Generally contraindicated during pregnancy. Generally contraindicated in pediatric age. Severe renal insufficiency (creatinine clearance less than 30ml / min). Dosage Adults: 1 teaspoon as an antacid; as a laxative 1 teaspoon '; as a purgative 1 tbsp. Children. Between 6 and 12 years: half the doses. Dilute the powder in half a glass of water and swallow. The correct dose is the minimum sufficient to produce an easy evacuation of soft faeces. It is advisable to initially use the minimum doses provided. When necessary, the dose can then be increased, but without ever exceeding the maximum indicated. Take preferably in the evening. Laxatives should be used as infrequently as possible and for no more than seven days. Use for longer periods of time requires a doctor's prescription after adequate evaluation of the individual case. Ingest together with an adequate quantity of water (a large glass). A diet rich in liquids favors the effect of the medicine. It is not recommended to administer the drug to children younger than 6 years. storage This medicine does not require any special storage conditions. Warnings The abuse of laxatives (frequent or prolonged use or with excessive doses) can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In the most severe cases the onset of dehydration or hypokalaemia is possible which can cause cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment with cardiac glycosides, diuretics or corticosteroids. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). Precautions for use: in children under the age of 12 the medicine can be used only after consulting your doctor. The treatment of chronic or recurrent constipation always requires the intervention of the doctor for the diagnosis, the prescription of drugs and the surveillance during the course of therapy. Consult your doctor when the need for the laxative derives from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) lasting more than two weeks or when the use of the laxative fails to produce effects. It is also advisable that elderly people or those in poor health conditions consult their doctor before using the medicine. To be used only on medical prescription in case of kidney disease. In case of diabetes or low-calorie diets, it should be borne in mind that the product contains sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency should not take the medicine. For the effervescent powder: in the case of low-sodium diets, it must be borne in mind that the product contains sodium salts. Interactions Laxatives can reduce the time spent in the intestine, and therefore the absorption, of other drugs administered simultaneously orally. Therefore, avoid taking laxatives and other drugs at the same time: after taking a medicine, leave an interval of at least 2 hours before taking the laxative. Magnesium hydroxide, like all antacids, should not be taken at the same time as antibiotics of the tetracycline class as it reduces their absorption. Milk or antacids can change the effect of the medicine; leave an interval of at least an hour before taking the laxative. Association to be avoided Tetracyclines: formation of insoluble complexes with reduction of the absorption and activity of these antibiotics. Association not recommended. Quinidine: increased plasma rates of quinidine and risk of overdose due to decreased excretion. Associations requiring precautions for use. Indomethacin, phosphorus, dexamethasone, digitalis, iron salts, nitrofurantoin, lincomycin: decreased absorption in the digestive system.